Le nœud de Toronto du C3G a développé MetaFusion, un outil de méta-appel flexible qui agrège les résultats de plusieurs logiciels d’appel de fusion.

Pendant mes études de baccalauréat en génie logiciel à l’Université McGill, j’ai intégré le Centre canadien de génomique computationnelle (CCG) en tant que stagiaire en 2020.

Les personnes vivant avec le VIH (PVVIH) présentent un risque accru de tuberculose (TB). La tuberculose associée au VIH résulte souvent d’une infection récente par Mycobacterium tuberculosis (Mtb) suivie d’une progression rapide vers la maladie.

Recently, using mice with different combinations of genetic and phenotypic sex, we were able to identify sex-associated differentially methylated regions (sDMRs) that depended on the sex phenotype (see this related study).

In recognition of Transposons Day 2021 (June 16th), let’s take a look at the importance of active mobile genomic elements (once called “junk DNA”) to human health and diseases.

Using big data techniques to analyze the function of human genes is already helping develop treatments tailored to individual patients. The more data researchers can access from across the world, the better chances of treating even rare diseases. But privacy and consent regulations differ by country, making sharing this information across borders slow and frustrating.

As a Bioinformatician, often I get to work with PDX cancer samples. I’ve recently been reading about samples containing genome admixture, and was revisiting strategies that we commonly use for analyzing these biological data. Presented here is a summary of the existing software tools used for this purpose.