A beginner's Guide to Manual Curation of Transposable Elements In the study of transposable elements (TEs), the generation of a high confidence set of consensus sequences that represent the diversity of TEs found in a given genome is a key step in the path to investigating these fascinating genomic [Read more]
C3G Bioinformatics Platform at the Rosalind and Morris Goodman Cancer Institute With next-generation sequencing and other high-throughput technologies revolutionizing life sciences and health care research, data processing and interpretation, rather than data production, has become the major limiting factor for discovery and innovation. Large genomics centers, and increasingly smaller [Read more]
A Coordinated Progression of Progenitor Cell States Initiates Urinary Tract Development Oraly Sanchez-Ferras from the Goodman Cancer Research Centre recently published a paper in Nature Communications. She reveals how the formation of tissues proceeds through a progression of different progenitors. This understanding is important for the generation of organ [Read more]
Architecture beyond buildings Hi there! Could you please tell us a little bit about yourself and what you do at C3G? My name is Ksenia Zaytseva and I am a Data Architect within the Data Team at C3G. I have a Master’s degree in Information Science. Before C3G I worked [Read more]
McGill and Genome Canada announce new Canadian SARS-CoV-2 Data Portal The development and implementation of the new Canadian SARS-CoV-2 Data Portal will be led by McGill University’s Dr. Guillaume Bourque, Professor in the Department of Human Genetics, and Director, Canadian Center for Computational Genomics. The Data Portal will manage and facilitate [Read more]
Matching single cells to a reference cell type By Maxime Caron For more than a decade it has been possible to profile the transcriptome of single cells and numerous analytical methods have emerged over these years [1]. C3G is currently undertaking one such single cell transcriptomic project. A useful analysis [Read more]
In a Bioinformatician’s Shoes Meet Hector in this short video interview as he shares with us his passion as a bioinformatician and the exciting challenges he faces at C3G in the era of Covid19. One of his many projects tracks Covid19 mutations and variant evolutions in near real-time to [Read more]
Don’t Skip the Repeats By Jeffrey Hyacinthe Junk DNA: vestigial remains or the genome’s dark matter? For a long time, genetic repeats and transposable elements were characterized as such – useless, nuisances and unknowable. There was some sense to that vision. Once the 20 000 genes of the human genome [Read more]
Denmark’s Minkstermination by Qinwei Zhuang The decision announced by the Danish prime minister, Mette Frederiksen, on November 4th to destroy all minks in the northern country is projected to result in the destruction of more than 15 million minks. The Danish government claimed their decision was supported by evidence that [Read more]
COVID-19 didn’t cancel these summer internships by David Brownlee With economies locked down this past summer and companies reluctant to hire, for many students, internship opportunities looked rather grim. Despite the shutdown of the McGill campus, The Canadian Collaborative Centre for Genomics and Biomedical data(C3G) shifted gears and revved up [Read more]
