In recognition of Transposons Day 2021 (June 16th), let’s take a look at the importance of active mobile genomic elements (once called “junk DNA”) to human health and diseases.
Continue readingHow do jumping genes contribute to human diversity?
Why better Data Sharing means better health Care
Using big data techniques to analyze the function of human genes is already helping develop treatments tailored to individual patients. The more data researchers can access from across the world, the better chances of treating even rare diseases. But privacy and consent regulations differ by country, making sharing this information across borders slow and frustrating.
Continue readingDisambiguating mixed-species of graft samples
As a Bioinformatician, often I get to work with PDX cancer samples. I’ve recently been reading about samples containing genome admixture, and was revisiting strategies that we commonly use for analyzing these biological data. Presented here is a summary of the existing software tools used for this purpose.
Continue readingCommon bioinformatics software maintained by C3G
There is a huge library of common bioinformatics software available on Compute Canada resources via the modules maintained by C3G staff and distributed via the CernVM-File System (CVMFS). Despite the breadth of the C3G CVMFS library, there may be times when using the provided software isn’t ideal.
Continue readingMcGill researchers awarded Azrieli Science Grant for RNA and the brain
Dr. Wayne Sossin, Professor at The Montreal Neurological Institute, McGill University, Montreal, has been awarded a grant through the Azrieli Science Grants Program as principal investigator for a research project titled “Determining how stalled polysomes are generated for transport in RNA granules and regulated local translation”.
Continue readingArchitecture beyond buildings
My name is Ksenia Zaytseva and I am a Data Architect within the Data Team at C3G. I have a Master’s degree in Information Science. Before C3G I worked in a variety of academic research disciplines building data and metadata management systems mostly for their Open Data initiatives.
Continue readingMcGill and Genome Canada announce new Canadian SARS-CoV-2 Data Portal
The development and implementation of the new Canadian SARS-CoV-2 Data Portal will be led by McGill University’s Dr. Guillaume Bourque, Professor in the Department of Human Genetics, and Director, Canadian Center for Computational Genomics.
Continue readingMatching single cells to a reference cell type
For more than a decade it has been possible to profile the transcriptome of single cells and numerous analytical methods have emerged over these years [1]. C3G is currently undertaking one such single cell transcriptomic project.
Continue readingIn a Bioinformatician’s Shoes
Meet Hector in this short video interview as he shares with us his passion as a bioinformatician and the exciting challenges he faces at C3G in the era of Covid19.
Continue readingDon’t Skip the Repeats
Junk DNA: vestigial remains or the genome’s dark matter? For a long time, genetic repeats and transposable elements were characterized as such – useless, nuisances and unknowable.
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