Below you will find scientific publications authored by our members or those enabled by our platform services.

102 entries « 1 of 3 »


Sanchez-Ferras, Oraly; Pacis, Alain; Sotiropoulou, Maria; Zhang, Yuhong; Wang, Yu Chang; Bourgey, Mathieu; Bourque, Guillaume; Ragoussis, Jiannis; Bouchard, Maxime

A coordinated progression of progenitor cell states initiates urinary tract development Journal Article

In: Nature Communications, vol. 12, no. 1, pp. 2627, 2021, ISSN: 2041-1723, (Number: 1 Publisher: Nature Publishing Group).

Abstract | Links | BibTeX | Tags: C3G, genomics, RNA-seq

Ward, Christopher M; Aumann, Roswitha A; Whitehead, Mark A; Nikolouli, Katerina; Leveque, Gary; Gouvi, Georgia; Fung, Elisabeth; Reiling, Sarah J; Djambazian, Haig; Hughes, Margaret A; Whiteford, Sam; Caceres-Barrios, Carlos; Nguyen, Thu N M; Choo, Amanda; Crisp, Peter; Sim, Sheina B; Geib, Scott M; Marec, František; Häcker, Irina; Ragoussis, Jiannis; Darby, Alistair C; Bourtzis, Kostas; Baxter, Simon W; Schetelig, Marc F

White pupae phenotype of tephritids is caused by parallel mutations of a MFS transporter Journal Article

In: Nature Communications, vol. 12, no. 1, pp. 491, 2021, ISSN: 2041-1723, (Number: 1 Publisher: Nature Publishing Group).

Abstract | Links | BibTeX | Tags:

Lee, Robert C; Farfan-Caceres, Lina; Debler, Johannes W; Williams, Angela H; Syme, Robert A; Henares, Bernadette M

Reference genome assembly for Australian Ascochyta lentis isolate Al4 Journal Article

In: G3 GenestextbarGenomestextbarGenetics, vol. 11, no. jkab006, 2021, ISSN: 2160-1836.

Abstract | Links | BibTeX | Tags:

Dursi, Jonathan L; Bozoky, Zoltan; de Borja, Richard; Li, Jimmy; Bujold, David; Lipski, Adam; Rashid, Shaikh Farhan; Sethi, Amanjeev; Memon, Neelam; Naidoo, Dashaylan; Coral-Sasso, Felipe; Wong, Matthew; Quirion, P -O; Lu, Zhibin; Agarwal, Samarth; Pavlov, Kat; Ponomarev, Andrew; Husic, Mia; Pace, Krista; Palmer, Samantha L; Grover, Stephanie A; Hakgor, Sevan; Siu, Lillian L; Malkin, David; Virtanen, Carl; Pugh, Trevor J; Jacques, Pierre-Étienne; Joly, Yann; Jones, Steven J M; Bourque, Guillaume; Brudno, Michael

CanDIG: Secure Federated Genomic Queries and Analyses Across Jurisdictions Journal Article

In: bioRxiv, pp. 2021.03.30.434101, 2021, (Publisher: Cold Spring Harbor Laboratory Section: New Results).

Abstract | Links | BibTeX | Tags:

Lopez Leyva, Lilian; Gonzalez, Emmanuel; Li, Chen; Ajeeb, Tamara; Solomons, Noel W; Agellon, Luis B; Scott, Marilyn E; Koski, Kristine G

Human Milk Microbiota in an Indigenous Population Is Associated with Maternal Factors, Stage of Lactation, and Breastfeeding Practices Journal Article

In: Current Developments in Nutrition, vol. 5, no. nzab013, 2021, ISSN: 2475-2991.

Abstract | Links | BibTeX | Tags:

El-Far, Mohamed; Durand, Madeleine; Turcotte, Isabelle; Larouche-Anctil, Etienne; Sylla, Mohamed; Zaidan, Sarah; Chartrand-Lefebvre, Carl; Bunet, Rémi; Ramani, Hardik; Sadouni, Manel; Boldeanu, Irina; Chamberland, Annie; Lesage, Sylvie; Baril, Jean-Guy; Trottier, Benoit; Thomas, Réjean; Gonzalez, Emmanuel; Filali-Mouhim, Ali; Goulet, Jean-Philippe; Martinson, Jeffrey A; Kassaye, Seble; Karim, Roksana; Kizer, Jorge R; French, Audrey L; Gange, Stephen J; Ancuta, Petronela; Routy, Jean-Pierre; Hanna, David B; Kaplan, Robert C; Chomont, Nicolas; Landay, Alan L; Tremblay, Cécile L

Upregulated IL-32 Expression And Reduced Gut Short Chain Fatty Acid Caproic Acid in People Living With HIV With Subclinical Atherosclerosis Journal Article

In: Frontiers in Immunology, vol. 12, 2021, ISSN: 1664-3224, (Publisher: Frontiers).

Abstract | Links | BibTeX | Tags: Atherosclerosis, CVD (cardio vascular disease), gut microbiome, HIV, IL-32, Inflammation, short-chain fatty acids

Brereton, N J B; Pitre, F E; Gonzalez, E

Reanalysis of the Mars500 experiment reveals common gut microbiome alterations in astronauts induced by long-duration confinement Journal Article

In: Computational and Structural Biotechnology Journal, vol. 19, pp. 2223–2235, 2021, ISSN: 2001-0370.

Abstract | Links | BibTeX | Tags: 16S rRNA gene, Astronaut health, Mars, Microbiome, Space science


Chehboun, Salma; Leiva-Torres, Gabriel André; Charbonneau, Benoît; Eveleigh, Robert; Bourque, Guillaume; Vidal, Silvia Marina

A point mutation in the linker domain of mouse STAT5A is associated with impaired NK-cell regulation Journal Article

In: Genes & Immunity, vol. 21, no. 2, pp. 136–141, 2020, ISSN: 1476-5470, (Number: 2 Publisher: Nature Publishing Group).

Abstract | Links | BibTeX | Tags:

Brereton, N J B; Gonzalez, E; Desjardins, D; Labrecque, M; Pitre, F E

Co-cropping with three phytoremediation crops influences rhizosphere microbiome community in contaminated soil Journal Article

In: Science of The Total Environment, vol. 711, pp. 135067, 2020, ISSN: 0048-9697.

Abstract | Links | BibTeX | Tags: 16S rRNA, Co-cropping, Metagenomics, Microbiome, Phytoremediation, Rhizosphere

Nikbakht, Hamid; Jessa, Selin; Sukhai, Mahadeo A; Arseneault, Madeleine; Zhang, Tong; Letourneau, Louis; Thomas, Mariam; Bourgey, Mathieu; Roehrl, Michael H A; Eveleigh, Robert; Chen, Eric X; Krzyzanowska, Monika; Moore, Malcolm J; Giesler, Amanda; Yu, Celeste; Bedard, Philippe L; Kamel-Reid, Suzanne; Majewski, Jacek; Siu, Lillian L; Riazalhosseini, Yasser; Graham, Donna M

Latency and interval therapy affect the evolution in metastatic colorectal cancer Journal Article

In: Scientific Reports, vol. 10, no. 1, pp. 581, 2020, ISSN: 2045-2322, (Number: 1 Publisher: Nature Publishing Group).

Abstract | Links | BibTeX | Tags:

Journal Article

In: 2020.

BibTeX | Tags:

Lee, Robert C; Farfan-Caceres, Lina M; Debler, Johannes W; Syme, Robert A

Characterization of Growth Morphology and Pathology, and Draft Genome Sequencing of Botrytis fabae, the Causal Organism of Chocolate Spot of Faba Bean (Vicia faba L.) Journal Article

In: Frontiers in Microbiology, vol. 11, 2020, ISSN: 1664-302X, (Publisher: Frontiers).

Abstract | Links | BibTeX | Tags: ascomycete, BGM, botrytis fabae, chocolate spot, faba bean, Grey mould, Lens culinaris, Lentil, Necrotroph, phytopathogen, Plant Pathogen, Vicia faba

Morfin, Nuria; Goodwin, Paul H; Guzman-Novoa, Ernesto

Interaction of field realistic doses of clothianidin and Varroa destructor parasitism on adult honey bee (Apis mellifera L.) health and neural gene expression, and antagonistic effects on differentially expressed genes Journal Article

In: PLOS ONE, vol. 15, no. 2, pp. e0229030, 2020, ISSN: 1932-6203, (Publisher: Public Library of Science).

Abstract | Links | BibTeX | Tags: Bees, Behavior, Gene expression, Honey bees, Insecticides, Invertebrate genomics, Mites, Parasitism

El-Sehemy, Ahmed; Selvadurai, Hayden; Ortin-Martinez, Arturo; Pokrajac, Neno; Mamatjan, Yasin; Tachibana, Nobuhiko; Rowland, Katherine; Lee, Lilian; Park, Nicole; Aldape, Kenneth; Dirks, Peter; Wallace, Valerie A

Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and Wnt Journal Article

In: The Journal of Clinical Investigation, vol. 130, no. 6, pp. 3069–3086, 2020, ISSN: 0021-9738, (Publisher: American Society for Clinical Investigation).

Links | BibTeX | Tags:

Moolhuijzen, Paula M; Muria-Gonzalez, Mariano Jordi; Syme, Robert; Rawlinson, Catherine; See, Pao Theen; Moffat, Caroline S; Ellwood, Simon R

Expansion and Conservation of Biosynthetic Gene Clusters in Pathogenic Pyrenophora spp. Journal Article

In: Toxins, vol. 12, no. 4, pp. 242, 2020, (Number: 4 Publisher: Multidisciplinary Digital Publishing Institute).

Abstract | Links | BibTeX | Tags: comparative genomics, necrotrophic fungal pathogen, NRPS, PKS, secondary metabolism, synteny

Choufani, Sanaa; Gibson, William T; Turinsky, Andrei L; Chung, Brian H Y; Wang, Tianren; Garg, Kopal; Vitriolo, Alessandro; Cohen, Ana S A; Cyrus, Sharri; Goodman, Sarah; Chater-Diehl, Eric; Brzezinski, Jack; Brudno, Michael; Ming, Luk Ho; White, Susan M; Lynch, Sally Ann; Clericuzio, Carol; Temple, Karen I; Flinter, Frances; McConnell, Vivienne; Cushing, Tom; Bird, Lynne M; Splitt, Miranda; Kerr, Bronwyn; Scherer, Stephen W; Machado, Jerry; Imagawa, Eri; Okamoto, Nobuhiko; Matsumoto, Naomichi; Testa, Guiseppe; Iascone, Maria; Tenconi, Romano; Caluseriu, Oana; Mendoza-Londono, Roberto; Chitayat, David; Cytrynbaum, Cheryl; Tatton-Brown, Katrina; Weksberg, Rosanna

DNA Methylation Signature for EZH2 Functionally Classifies Sequence Variants in Three PRC2 Complex Genes Journal Article

In: The American Journal of Human Genetics, vol. 106, no. 5, pp. 596–610, 2020, ISSN: 0002-9297, 1537-6605, (Publisher: Elsevier).

Links | BibTeX | Tags: DNA methylation signature, EED, intellectual disability, overgrowth syndromes, SUZ12

Caron, Maxime; St-Onge, Pascal; Sontag, Thomas; Wang, Yu Chang; Richer, Chantal; Ragoussis, Ioannis; Sinnett, Daniel; Bourque, Guillaume

Single-cell analysis of childhood leukemia reveals a link between developmental states and ribosomal protein expression as a source of intra-individual heterogeneity Journal Article

In: Scientific Reports, vol. 10, no. 1, pp. 8079, 2020, ISSN: 2045-2322, (Number: 1 Publisher: Nature Publishing Group).

Abstract | Links | BibTeX | Tags:

Groza, Cristian; Kwan, Tony; Soranzo, Nicole; Pastinen, Tomi; Bourque, Guillaume

Personalized and graph genomes reveal missing signal in epigenomic data Journal Article

In: Genome Biology, vol. 21, no. 1, pp. 124, 2020, ISSN: 1474-760X.

Abstract | Links | BibTeX | Tags: ChIP-seq, De novo assembly, Epigenomics, Genome graphs, Modified reference, Personalized genomes, Reference bias

Tremblay, Karine; Gaudet, Daniel; Khoury, Etienne; Brisson, Diane

Dissection of Clinical and Gene Expression Signatures of Familial versus Multifactorial Chylomicronemia Journal Article

In: Journal of the Endocrine Society, vol. 4, no. bvaa056, 2020, ISSN: 2472-1972.

Abstract | Links | BibTeX | Tags:

Zhuang, Qinwei Kim-Wee; Galvez, Jose Hector; Xiao, Qian; AlOgayil, Najla; Hyacinthe, Jeffrey; Taketo, Teruko; Bourque, Guillaume; Naumova, Anna K

Sex Chromosomes and Sex Phenotype Contribute to Biased DNA Methylation in Mouse Liver Journal Article

In: Cells, vol. 9, no. 6, pp. 1436, 2020, (Number: 6 Publisher: Multidisciplinary Digital Publishing Institute).

Abstract | Links | BibTeX | Tags: DNA methylation, Gene expression, mouse liver, sex-chromosome complement, sexual dimorphism, whole genome bisulfite sequencing

Mohanraj, Suluxan; Díaz-Mejía, Javier J; Pham, Martin D; Elrick, Hillary; Husić, Mia; Rashid, Shaikh; Luo, Ping; Bal, Prabnur; Lu, Kevin; Patel, Samarth; Mahalanabis, Alaina; Naidas, Alaine; Christensen, Erik; Croucher, Danielle; Richards, Laura M; Shooshtari, Parisa; Brudno, Michael; Ramani, Arun K; Pugh, Trevor J

CReSCENT: CanceR Single Cell ExpressioN Toolkit Journal Article

In: Nucleic Acids Research, vol. 48, no. W1, pp. W372–W379, 2020, ISSN: 0305-1048.

Abstract | Links | BibTeX | Tags:

Couturier, Charles P; Ayyadhury, Shamini; Le, Phuong U; Nadaf, Javad; Monlong, Jean; Riva, Gabriele; Allache, Redouane; Baig, Salma; Yan, Xiaohua; Bourgey, Mathieu; Lee, Changseok; Wang, Yu Chang David; Yong, V Wee; Guiot, Marie-Christine; Najafabadi, Hamed; Misic, Bratislav; Antel, Jack; Bourque, Guillaume; Ragoussis, Jiannis; Petrecca, Kevin

Single-cell RNA-seq reveals that glioblastoma recapitulates a normal neurodevelopmental hierarchy Journal Article

In: Nature Communications, vol. 11, no. 1, pp. 3406, 2020, ISSN: 2041-1723, (Number: 1 Publisher: Nature Publishing Group).

Abstract | Links | BibTeX | Tags:

Khazaei, Sima; Jay, Nicolas De; Deshmukh, Shriya; Hendrikse, Liam D; Jawhar, Wajih; Chen, Carol C L; Mikael, Leonie G; Faury, Damien; Marchione, Dylan M; Lanoix, Joel; Bonneil, Éric; Ishii, Takeaki; Jain, Siddhant U; Rossokhata, Kateryna; Sihota, Tianna S; Eveleigh, Robert; Lisi, Véronique; Harutyunyan, Ashot S; Jung, Sungmi; Karamchandani, Jason; Dickson, Brendan C; Turcotte, Robert; Wunder, Jay S; Thibault, Pierre; Lewis, Peter W; Garcia, Benjamin A; Mack, Stephen C; Taylor, Michael D; Garzia, Livia; Kleinman, Claudia L; Jabado, Nada

H3.3 G34W Promotes Growth and Impedes Differentiation of Osteoblast-Like Mesenchymal Progenitors in Giant Cell Tumor of Bone Journal Article

In: Cancer Discovery, vol. 10, no. 12, pp. 1968–1987, 2020, ISSN: 2159-8274, 2159-8290, (Publisher: American Association for Cancer Research Section: Research Articles).

Abstract | Links | BibTeX | Tags:

Wang, Yifan; Park, Jin Yong Patrick; Pacis, Alain; Denroche, Robert E; Jang, Gun Ho; Zhang, Amy; Cuggia, Adeline; Domecq, Celine; Monlong, Jean; Raitses-Gurevich, Maria; Grant, Robert C; Borgida, Ayelet; Holter, Spring; Stossel, Chani; Bu, Simeng; Masoomian, Mehdi; Lungu, Ilinca M; Bartlett, John M S; Wilson, Julie M; Gao, Zu-Hua; Riazalhosseini, Yasser; Asselah, Jamil; Bouganim, Nathaniel; Cabrera, Tatiana; Boucher, Louis-Martin; Valenti, David; Biagi, James; Greenwood, Celia M T; Polak, Paz; Foulkes, William D; Golan, Talia; O'Kane, Grainne M; Fischer, Sandra E; Knox, Jennifer J; Gallinger, Steven; Zogopoulos, George

A Preclinical Trial and Molecularly Annotated Patient Cohort Identify Predictive Biomarkers in Homologous Recombination–deficient Pancreatic Cancer Journal Article

In: Clinical Cancer Research, vol. 26, no. 20, pp. 5462–5476, 2020, ISSN: 1078-0432, 1557-3265, (Publisher: American Association for Cancer Research Section: Translational Cancer Mechanisms and Therapy).

Abstract | Links | BibTeX | Tags:

Moreau, Clara A; Urchs, Sebastian G W; Kuldeep, Kumar; Orban, Pierre; Schramm, Catherine; Dumas, Guillaume; Labbe, Aurélie; Huguet, Guillaume; Douard, Elise; Quirion, Pierre-Olivier; Lin, Amy; Kushan, Leila; Grot, Stephanie; Luck, David; Mendrek, Adrianna; Potvin, Stephane; Stip, Emmanuel; Bourgeron, Thomas; Evans, Alan C; Bearden, Carrie E; Bellec, Pierre; Jacquemont, Sebastien

Mutations associated with neuropsychiatric conditions delineate functional brain connectivity dimensions contributing to autism and schizophrenia Journal Article

In: Nature Communications, vol. 11, no. 1, pp. 5272, 2020, ISSN: 2041-1723, (Number: 1 Publisher: Nature Publishing Group).

Abstract | Links | BibTeX | Tags:


Robert Eveleigh, Guillaume Bourque

A point mutation in the linker domain of mouse STAT5A is associated with impaired NK-cell regulation Journal Article

In: 2019.

Abstract | Links | BibTeX | Tags: Immunogenetics, Innate immune cells

Ana S. Guerreiro Stucklin, Scott Ryall

Alterations in ALK/ROS1/NTRK/MET drive a group of infantile hemispheric gliomas Journal Article

In: 2019.

Abstract | Links | BibTeX | Tags: Cancer genomics, Molecular medicine

Turinsky, Andrei L; Butcher, Darci T; Choufani, Sanaa; Weksberg, Rosanna; Brudno, Michael

Don’t brush off buccal data heterogeneity Journal Article

In: Epigenetics, vol. 14, no. 2, pp. 109-117, 2019, (PMID: 30821575).

Links | BibTeX | Tags:

Page, Donna J; Miossec, Matthieu J; Williams, Simon G; Monaghan, Richard M; Fotiou, Elisavet; Cordell, Heather J; Sutcliffe, Louise; Topf, Ana; Bourgey, Mathieu; Bourque, Guillaume; Eveleigh, Robert; Dunwoodie, Sally L; Winlaw, David S; Bhattacharya, Shoumo; Breckpot, Jeroen; Devriendt, Koenraad; Gewillig, Marc; Brook, David J; Setchfield, Kerry J; Bu’Lock, Frances A; O’Sullivan, John; Stuart, Graham; Bezzina, Connie R; Mulder, Barbara J M; Postma, Alex V; Bentham, James R; Baron, Martin; Bhaskar, Sanjeev S; Black, Graeme C; Newman, William G; Hentges, Kathryn E; Lathrop, Mark G; Santibanez-Koref, Mauro; Keavney, Bernard D

Whole Exome Sequencing Reveals the Major Genetic Contributors to Nonsyndromic Tetralogy of Fallot Journal Article

In: Circulation Research, vol. 124, no. 4, pp. 553-563, 2019.

Links | BibTeX | Tags:

Laperle, Jonathan; Hébert-Deschamps, Simon; Raby, Joanny; de Lima Morais, David A; Barrette, Michel; Bujold, David; Bastin, Charlotte; Robert, Marc-Antoine; Nadeau, Jean-François; Harel, Marie; Nordell-Markovits, Alexei; Veilleux, Alain; Bourque, Guillaume; Jacques, Pierre-Étienne

The epiGenomic Efficient Correlator (epiGeEC) tool allows fast comparison of user datasets with thousands of public epigenomic datasets Journal Article

In: Bioinformatics, vol. 35, no. 4, pp. 674–676, 2019, ISSN: 1367-4803.

Abstract | Links | BibTeX | Tags:

Shokoohi, Farhad; Stephens, David A; Bourque, Guillaume; Pastinen, Tomi; Greenwood, Celia M T; Labbe, Aurélie

A hidden markov model for identifying differentially methylated sites in bisulfite sequencing data Journal Article

In: Biometrics, vol. 75, no. 1, pp. 210–221, 2019, ISSN: 1541-0420, (_eprint:

Abstract | Links | BibTeX | Tags: Blood cell-separated data, Differentially methylated region, Next-generation sequencing, Read-depth

Choufani, Sanaa; Turinsky, Andrei L; Melamed, Nir; Greenblatt, Ellen; Brudno, Michael; Bérard, Anick; Fraser, William D; Weksberg, Rosanna; Trasler, Jacquetta; Monnier, Patricia; cohort study group, 3D

Impact of assisted reproduction, infertility, sex and paternal factors on the placental DNA methylome Journal Article

In: Human Molecular Genetics, vol. 28, no. 3, pp. 372–385, 2019, ISSN: 0964-6906.

Abstract | Links | BibTeX | Tags:

Cvetkovska, Marina; Orgnero, Shane; Hüner, Norman P A; Smith, David Roy

The enigmatic loss of light-independent chlorophyll biosynthesis from an Antarctic green alga in a light-limited environment Journal Article

In: New Phytologist, vol. 222, no. 2, pp. 651–656, 2019, ISSN: 1469-8137, (_eprint:

Links | BibTeX | Tags: Chlamydomonas sp. UWO241, chlorophyll, DPOR, photosynthesis, psychrophile

Journal Article

In: Epigenetics, vol. 14, no. 2, pp. 109–117, 2019.

BibTeX | Tags: buccal epithelial cells, DNA methylation, epigenetics, tissue heterogeneity

Untereiner, Ashley; Abdo, Shaaban; Bhattacharjee, Alpana; Gohil, Himaben; Pourasgari, Farzaneh; Ibeh, Neke; Lai, Mi; Batchuluun, Battsetseg; Wong, Anthony; Khuu, Nicholas; Liu, Ying; Rijjal, Dana Al; Winegarden, Neil; Virtanen, Carl; Orser, Beverley A; Cabrera, Over; Varga, Gabor; Rocheleau, Jonathan; Dai, Feihan F; Wheeler, Michael B

GABA promotes β-cell proliferation, but does not overcome impaired glucose homeostasis associated with diet-induced obesity Journal Article

In: The FASEB Journal, vol. 33, no. 3, pp. 3968–3984, 2019, ISSN: 1530-6860, (_eprint:

Abstract | Links | BibTeX | Tags: diet-induced obesity, GABAA receptor, glucose tolerance, insulin secretion, single cell RNA-seq

Sukhai, Mahadeo A; Misyura, Maksym; Thomas, Mariam; Garg, Swati; Zhang, Tong; Stickle, Natalie; Virtanen, Carl; Bedard, Philippe L; Siu, Lillian L; Smets, Tina; Thijs, Gert; Vooren, Steven Van; Kamel-Reid, Suzanne; Stockley, Tracy L

Somatic Tumor Variant Filtration Strategies to Optimize Tumor-Only Molecular Profiling Using Targeted Next-Generation Sequencing Panels Journal Article

In: The Journal of Molecular Diagnostics, vol. 21, no. 2, pp. 261–273, 2019, ISSN: 1525-1578, (Publisher: Elsevier).

Abstract | Links | BibTeX | Tags:

Gonorazky, Hernan D; Naumenko, Sergey; Ramani, Arun K; Nelakuditi, Viswateja; Mashouri, Pouria; Wang, Peiqui; Kao, Dennis; Ohri, Krish; Viththiyapaskaran, Senthuri; Tarnopolsky, Mark A; Mathews, Katherine D; Moore, Steven A; Osorio, Andres N; Villanova, David; Kemaladewi, Dwi U; Cohn, Ronald D; Brudno, Michael; Dowling, James J

Expanding the Boundaries of RNA Sequencing as a Diagnostic Tool for Rare Mendelian Disease Journal Article

In: The American Journal of Human Genetics, vol. 104, no. 3, pp. 466–483, 2019, ISSN: 0002-9297, 1537-6605, (Publisher: Elsevier).

Links | BibTeX | Tags: diagnostics, Mendelian disease, muscular dystrophy, myotubes, RNA-seq, Transcriptomics, transdifferentiation

Chong, Jasmine; Yamamoto, Mai; Xia, Jianguo

MetaboAnalystR 2.0: From Raw Spectra to Biological Insights Journal Article

In: Metabolites, vol. 9, no. 3, pp. 57, 2019, (Number: 3 Publisher: Multidisciplinary Digital Publishing Institute).

Abstract | Links | BibTeX | Tags: enrichment analysis, global metabolomics, LC-MS, pathway analysis, spectra processing

Zhou, Guangyan; Soufan, Othman; Ewald, Jessica; Hancock, Robert E W; Basu, Niladri; Xia, Jianguo

NetworkAnalyst 3.0: a visual analytics platform for comprehensive gene expression profiling and meta-analysis Journal Article

In: Nucleic Acids Research, vol. 47, no. W1, pp. W234–W241, 2019, ISSN: 0305-1048.

Abstract | Links | BibTeX | Tags:

Gonzalez, Emmanuel; Pitre, Frederic E; Brereton, Nicholas J B

ANCHOR: a 16S rRNA gene amplicon pipeline for microbial analysis of multiple environmental samples Journal Article

In: Environmental Microbiology, vol. 21, no. 7, pp. 2440–2468, 2019, ISSN: 1462-2920, (_eprint:

Abstract | Links | BibTeX | Tags:

Breeze, Charles E; Reynolds, Alex P; van Dongen, Jenny; Dunham, Ian; Lazar, John; Neph, Shane; Vierstra, Jeff; Bourque, Guillaume; Teschendorff, Andrew E; Stamatoyannopoulos, John A; Beck, Stephan

eFORGE v2.0: updated analysis of cell type-specific signal in epigenomic data Journal Article

In: Bioinformatics, vol. 35, no. 22, pp. 4767–4769, 2019, ISSN: 1367-4803.

Abstract | Links | BibTeX | Tags:

Bourgey, Mathieu; Dali, Rola; Eveleigh, Robert; Chen, Kuang Chung; Letourneau, Louis; Fillon, Joel; Michaud, Marc; Caron, Maxime; Sandoval, Johanna; Lefebvre, Francois; Leveque, Gary; Mercier, Eloi; Bujold, David; Marquis, Pascale; Van, Patrick Tran; Anderson de Lima Morais, David; Tremblay, Julien; Shao, Xiaojian; Henrion, Edouard; Gonzalez, Emmanuel; Quirion, Pierre-Olivier; Caron, Bryan; Bourque, Guillaume

GenPipes: an open-source framework for distributed and scalable genomic analyses Journal Article

In: GigaScience, vol. 8, no. giz037, 2019, ISSN: 2047-217X.

Abstract | Links | BibTeX | Tags:

Morou, Antigoni; Brunet-Ratnasingham, Elsa; Dubé, Mathieu; Charlebois, Roxanne; Mercier, Eloi; Darko, Sam; Brassard, Nathalie; Nganou-Makamdop, Krystelle; Arumugam, Sahaana; Gendron-Lepage, Gabrielle; Yang, Lifei; Niessl, Julia; Baxter, Amy E; Billingsley, James M; Rajakumar, Premeela A; Lefebvre, François; Johnson, Paul R; Tremblay, Cécile; Routy, Jean-Pierre; Wyatt, Richard T; Finzi, Andrés; Douek, Daniel C; Kaufmann, Daniel E

Altered differentiation is central to HIV-specific CD4 + Ŧ cell dysfunction in progressive disease Journal Article

In: Nature Immunology, vol. 20, no. 8, pp. 1059–1070, 2019, ISSN: 1529-2916, (Number: 8 Publisher: Nature Publishing Group).

Abstract | Links | BibTeX | Tags:

Siu, M T; Butcher, D T; Turinsky, A L; Cytrynbaum, C; Stavropoulos, D J; Walker, S; Caluseriu, O; Carter, M; Lou, Y; Nicolson, R; Georgiades, S; Szatmari, P; Anagnostou, E; Scherer, S W; Choufani, S; Brudno, M; Weksberg, R

Functional DNA methylation signatures for autism spectrum disorder genomic risk loci: 16p11.2 deletions and CHD8 variants Journal Article

In: Clinical Epigenetics, vol. 11, no. 1, pp. 103, 2019, ISSN: 1868-7083.

Abstract | Links | BibTeX | Tags: Autism spectrum disorder, DNA methylation, epigenetics, Genetic stratification, Genomic variants, Heterogeneity

Chang, Matthew L; Moussette, Sanny; Gamero-Estevez, Enrique; Gálvez, José Héctor; Chiwara, Victoria; Gupta, Indra R; Ryan, Aimee K; Naumova, Anna K

Regulatory interaction between the ZPBP2-ORMDL3/Zpbp2-Ormdl3 region and the circadian clock Journal Article

In: PLOS ONE, vol. 14, no. 9, pp. e0223212, 2019, ISSN: 1932-6203, (Publisher: Public Library of Science).

Abstract | Links | BibTeX | Tags: Asthma, Circadian oscillators, Circadian rhythms, Gene expression, Gene regulation, Genetic oscillators, Ileum, Transcriptional control

Grajcarek, Janin; Monlong, Jean; Nishinaka-Arai, Yoko; Nakamura, Michiko; Nagai, Miki; Matsuo, Shiori; Lougheed, David; Sakurai, Hidetoshi; Saito, Megumu K; Bourque, Guillaume; Woltjen, Knut

Genome-wide microhomologies enable precise template-free editing of biologically relevant deletion mutations Journal Article

In: Nature Communications, vol. 10, no. 1, pp. 4856, 2019, ISSN: 2041-1723, (Number: 1 Publisher: Nature Publishing Group).

Abstract | Links | BibTeX | Tags:

Minerbi, Amir; Gonzalez, Emmanuel; Brereton, Nicholas J B; Anjarkouchian, Abraham; Dewar, Ken; Fitzcharles, Mary-Ann; Chevalier, Stéphanie; Shir, Yoram

Altered microbiome composition in individuals with fibromyalgia Journal Article

In: PAIN, vol. 160, no. 11, pp. 2589–2602, 2019, ISSN: 0304-3959.

Abstract | Links | BibTeX | Tags:

Jessa, Selin; Blanchet-Cohen, Alexis; Krug, Brian; Vladoiu, Maria; Coutelier, Marie; Faury, Damien; Poreau, Brice; Jay, Nicolas De; Hébert, Steven; Monlong, Jean; Farmer, Todd W; Donovan, Laura K; Hu, Yixing; McConechy, Melissa K; Cavalli, Florence M G; Mikael, Leonie G; Ellezam, Benjamin; Richer, Maxime; Allaire, Andréa; Weil, Alexander G; Atkinson, Jeffrey; Farmer, Jean-Pierre; Dudley, Roy W R; Larouche, Valerie; Crevier, Louis; Albrecht, Steffen; Filbin, Mariella G; Sartelet, Hervé; Lutz, Pierre-Eric; Nagy, Corina; Turecki, Gustavo; Costantino, Santiago; Dirks, Peter B; Murai, Keith K; Bourque, Guillaume; Ragoussis, Jiannis; Garzia, Livia; Taylor, Michael D; Jabado, Nada; Kleinman, Claudia L

Stalled developmental programs at the root of pediatric brain tumors Journal Article

In: Nature Genetics, vol. 51, no. 12, pp. 1702–1713, 2019, ISSN: 1546-1718, (Number: 12 Publisher: Nature Publishing Group).

Abstract | Links | BibTeX | Tags:

Saulnier, Katie M; Bujold, David; Dyke, Stephanie O M; Dupras, Charles; Beck, Stephan; Bourque, Guillaume; Joly, Yann

Benefits and barriers in the design of harmonized access agreements for international data sharing Journal Article

In: Scientific Data, vol. 6, no. 1, pp. 297, 2019, ISSN: 2052-4463, (Number: 1 Publisher: Nature Publishing Group).

Abstract | Links | BibTeX | Tags:

Sengar, Ameet S; Li, Hongbin; Zhang, Wenbo; Leung, Celeste; Ramani, Arun K; Saw, Ner Mu; Wang, Yongqian; Tu, YuShan; Ross, Joel P; Scherer, Stephen W; Ellis, James; Brudno, Michael; Jia, Zhengping; Salter, Michael W

Control of Long-Term Synaptic Potentiation and Learning by Alternative Splicing of the NMDA Receptor Subunit GluN1 Journal Article

In: Cell Reports, vol. 29, no. 13, pp. 4285–4294.e5, 2019, ISSN: 2211-1247, (Publisher: Elsevier).

Links | BibTeX | Tags: autism, GluN1, long-term potentiation, N1 cassette, NMDA Receptor, splicing

102 entries « 1 of 3 »