STOP-CoV: Examining COVID-19 vaccination responses across age groups As the rollout for COVID-19 vaccinations continues across Ontario the C3G Toronto Node has helped establish STOP-CoV (SafeTy and Efficacy of Preventative COVID Vaccines), a province-wide study to examine the differences in COVID-19 vaccine responses between younger and older individuals. Participants contribute to the study by completing a [Read more]
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Rare loss-of-function variants in type I IFN immunity genes are not associated with severe COVID-19 Host genetic factors related to COVID-19 susceptibility and outcomes are of great interest, as their identification could elucidate the mechanisms of SARS-CoV-2 infection and severity, thereby providing clues about potential therapeutic targets. A recent [Read more]
Anesthesia-related Tweets during COVID-19 Twitter has become a social media nexus for the sharing of information, and in an Anesthesia & Analgesia Journal article published in April 2021, members of C3G’s Toronto Node at SickKids examined the way Twitter was used to share anesthesia-related information during the COVID-19 pandemic. [Read more]
A Coordinated Progression of Progenitor Cell States Initiates Urinary Tract Development Oraly Sanchez-Ferras from the Goodman Cancer Research Centre recently published a paper in Nature Communications. She reveals how the formation of tissues proceeds through a progression of different progenitors. This understanding is important for the generation of organ [Read more]
Whole Genome STR Analysis By David Lougheed About Short Tandem Repeats In early 2021, Jeffrey Hyacinthe, another student here in Guillaume Bourque’s lab, wrote about repetitive sequences, focusing on transposable elements (TEs). Here I will discuss another type of repetitive sequence: short tandem repeats (STRs), also known as microsatellites. These [Read more]
New study analyzes different mechanisms in the establishment of sex-phenotype dependent methylation in mouse livers
New study analyzes different mechanisms in the establishment of sex-phenotype dependent methylation in mouse livers By Hector Galvez and Qinwei Zhuang AlOgayil, N., Bauermeister, K., Galvez, J.H. et al. Distinct roles of androgen receptor, estrogen receptor alpha, and BCL6 in the establishment of sex-biased DNA methylation in mouse liver. [Read more]
‘CHANGE’ through the eyes of a Business Analyst By Mary Ann Kizhakechethipuza “There is nothing more difficult to take in hand, more perilous to conduct or more uncertain in its success than to take the lead in the introduction of a new order of things.” – Niccolò Machiavelli The Business [Read more]
McGill researchers awarded Azrieli Science Grant for RNA and the brain Dr. Wayne Sossin, Professor at The Montreal Neurological Institute, McGill University, Montreal, has been awarded a grant through the Azrieli Science Grants Program as principal investigator for a research project titled “Determining how stalled polysomes are generated for [Read more]
Astronaut gut microbiome alterations induced by long-duration confinement Throughout long-duration spaceflight, maintaining astronaut health is crucial to the feasibility of a manned mission to Mars. In the longest controlled human confinement study conducted to date, the ground-based Mars500 experiment investigated long-duration health by isolating six astronauts for 520 days. [Read more]
Architecture beyond buildings Hi there! Could you please tell us a little bit about yourself and what you do at C3G? My name is Ksenia Zaytseva and I am a Data Architect within the Data Team at C3G. I have a Master’s degree in Information Science. Before C3G I worked [Read more]