Blog & News

A beginner’s Guide to Manual Curation of Transposable Elements

May 10, 2022 | Bioinformatics, Genomics, Technology, Transposable Elements

In the study of transposable elements (TEs), the generation of a high confidence set of consensus sequences that represent the diversity of TEs found in a given genome is a key step in the path to investigating these fascinating genomic elements.

C3G Bioinformatics Platform at the Rosalind and Morris Goodman Cancer Institute

May 10, 2022 | Bioinformatics, Genomics, Technology

With next-generation sequencing and other high-throughput technologies revolutionizing life sciences and health care research, data processing and interpretation, rather than data production, has become the major limiting factor for discovery and innovation. Large genomics centers, and increasingly smaller research labs, are facing significant data analysis challenges.

The SecureData4Health (SD4H) website is LIVE

February 3, 2022 | Technology

SecureData4Health (SD4H) launched its new website.

Gene fusion meta-calling with MetaFusion

February 3, 2022 | Genomics

The Toronto Node of C3G has developed MetaFusion, a flexible meta-calling tool that amalgamates outputs from any number of fusion callers. Designed to overcome inconsistencies among frequently used fusion callers, MetaFusion is among the first ensemble fusion calling tools currently available.

Working with Genomics Coming From a Pure Software Engineering Background

January 5, 2022 | Genomics

While pursuing a Bachelor of Science in Software Engineering at McGill University, I joined the Canadian Centre for Computational Genomics as an intern in 2020. I started working at the C3G with no background whatsoever in the field of computational genomics.

Understanding why persons living with HIV are at increased risk of tuberculosis

January 5, 2022 | Genomics

Persons living with HIV (PLWH) are at increased risk of tuberculosis (TB). HIV-associated TB is often the result of a recent infection with Mycobacterium tuberculosis (Mtb) followed by rapid progression to the disease.

Whole Genome STR Analysis

January 5, 2022 | Technology

In early 2021, Jeffrey Hyacinthe, another student here in Guillaume Bourque’s lab, wrote about repetitive sequences, focusing on transposable elements (TEs). Here I will discuss another type of repetitive sequence: short tandem repeats (STRs), also known as microsatellites.

A small number of early introductions seeded widespread transmission of SARS-CoV-2 in Quebec, Canada

December 16, 2021 | SARS-CoV-2

In April 2020, the Coronavirus Sequencing in Québec (CoVSeQ) consortium was assembled to sequence SARS-CoV-2 genomes in Québec to track viral introduction events and transmission within the province.

Adapting to remote and electronic means of patient care

December 16, 2021 | Technology

Electronic and remote means of healthcare have become a staple over the past year, and the Toronto Node of C3G has been involved in several efforts to facilitate and improve remote patient care.

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