C3G Receives $4.6 million in Funding from the Canadian Foundation for Innovation (CFI) and partner organizations
Enabling breakthroughs in biomedical and life science research Guillaume Bourque, Director of the Canadian Centre
Blog & News
A beginner’s Guide to Manual Curation of Transposable Elements
In the study of transposable elements (TEs), the generation of a high confidence set of consensus sequences that represent the diversity of TEs found in a given genome is a key step in the path to investigating these fascinating genomic elements.
C3G Bioinformatics Platform at the Rosalind and Morris Goodman Cancer Institute
With next-generation sequencing and other high-throughput technologies revolutionizing life sciences and health care research, data processing and interpretation, rather than data production, has become the major limiting factor for discovery and innovation. Large genomics centers, and increasingly smaller research labs, are facing significant data analysis challenges.
Gene fusion meta-calling with MetaFusion
The Toronto Node of C3G has developed MetaFusion, a flexible meta-calling tool that amalgamates outputs from any number of fusion callers. Designed to overcome inconsistencies among frequently used fusion callers, MetaFusion is among the first ensemble fusion calling tools currently available.
Working with Genomics Coming From a Pure Software Engineering Background
While pursuing a Bachelor of Science in Software Engineering at McGill University, I joined the Canadian Centre for Computational Genomics as an intern in 2020. I started working at the C3G with no background whatsoever in the field of computational genomics.
Understanding why persons living with HIV are at increased risk of tuberculosis
Persons living with HIV (PLWH) are at increased risk of tuberculosis (TB). HIV-associated TB is often the result of a recent infection with Mycobacterium tuberculosis (Mtb) followed by rapid progression to the disease.
Whole Genome STR Analysis
In early 2021, Jeffrey Hyacinthe, another student here in Guillaume Bourque’s lab, wrote about repetitive sequences, focusing on transposable elements (TEs). Here I will discuss another type of repetitive sequence: short tandem repeats (STRs), also known as microsatellites.
A small number of early introductions seeded widespread transmission of SARS-CoV-2 in Quebec, Canada
In April 2020, the Coronavirus Sequencing in Québec (CoVSeQ) consortium was assembled to sequence SARS-CoV-2 genomes in Québec to track viral introduction events and transmission within the province.