Covid-19 updates at C3G We would like to provide a quick update amidst the coronavirus pandemic. While our host institutions (McGill University, SickKids Toronto) have put various measures in placeto ensure the safety of our staff, our platform remains fully operational and available to support genomics research. Researchers should [Read more]
GenPipes: an open-source framework for distributed and scalable genomic analyses It started in June with the publication of our beloved GenPipes framework and set of NGS data analysis pipelines in GigaScience. We use these pipelines on a daily basis for data production and routine analysis and hope the community [Read more]
COVID-19 Resources Canada Canadian Centre for Computational Genomicshas been part of a group of volunteer researchers, students, activists and web developers, led by Guillaume Bourque of McGill Universityand Tara Moriarty of the University of Toronto, who created COVID-19 Resources Canada a website to facilitate the sharing of information, expertise [Read more]
Methylation signatures investigations The C3G Toronto node has also been involved in two projects to investigate methylation signatures for specific conditions. We have recently published a manuscript in BMC Medical Genomics in which we describe specific DNA methylation signatures for Nicolaides-Baraitser syndrome (NBS), a rare childhood condition that affects [Read more]
Altered differentiation is central to HIV-specific CD4+ T cell dysfunction in progressive disease Another noteworthy publication to which C3G members contributed as authors was published in Nature Immunology this summer. An important focus of the study was the comparison of HIV-specific CD4 T-cells subpopulations from patients who have undergone [Read more]
GSoC 2019 is over! Again this year, C3G was a Google Summer of Code organization. For people unfamiliar with it, GSoC is in Google’s own words: ” a global program that matches students up with open source, free software and technology-related organizations to write code and get paid to [Read more]
Altered microbiome composition in individuals with fibromyalgia This summer has also been very special for C3G’s metagenome specialist Emmanuel Gonzalez with a publication in Painhighlighting a strong potential link between the microbiome and fibromyalgia, a terrible and elusive disorder affecting a large fraction of the population. This study drew [Read more]
Infant Glioma: Characterizing the landscape of genetic drivers and their clinical impact Recently published in [Nature Communications], this paper presents work by members of the C3G Toronto node that integrates genomic and transcriptomic analyses to assess the molecular and clinical features of infant glioma patients. Examining single nucleotide variants, [Read more]
New partnership to unravel genetic sequence of SARS-CoV-2 virus in Quebec The Institut national de santé publique du Québec (INSPQ) and the McGill Genome Centre today announced they will partner to sequence the viral genomes of Quebec patients with COVID-19 disease. The collaboration, termed “Coronavirus Sequencing in Quebec,” (CoVSeQ) [Read more]
The ANCHOR pipeline by Emmanuel Gonzalez ANCHOR is a high-resolution metagenomics pipeline, the result of a multi-disciplinary collaboration between C3G and researchers at Institut de recherche en biologie végétale (IRBV) at Université de Montreal. Published in 2019 in the journal Environmental Microbiology, the pipeline demonstrated unprecedented accuracy in its [Read more]
