Consultez notre blogue pour resté informé à propos de nos événements à venir ainsi qu’aux plus récents développements dans le domaine de la génomique. Veuillez noter que les blogues sont publiés ici dans leur langue d’origine seulement. ForCasT: a fully integrated and open source pipeline to design CRISPR mutagenesis experiments ForCas Tool (ForCasT) is a comprehensive tool for the design, evaluation and collection of CRISPR/Cas9 guide RNAs and primers. Using robust parameters, it generates guide RNAs for target loci, assesses their quality for any potential off-target [Read more] Why better health care depends on improving data sharing- Two of McGill's leading experts on genomics discuss epigenetics, open science and personalized medicine The future of personalized medicine is dependent on data sharing, according to Yann Joly, Research Director of the Centre of Genomics and Policies (right); and Guillaume [Read more] Covid-19 updates at C3G We would like to provide a quick update amidst the coronavirus pandemic. While our host institutions (McGill University, SickKids Toronto) have put various measures in placeto ensure the safety of our staff, our platform remains fully operational and available to support genomics research. Researchers should [Read more] GenPipes: an open-source framework for distributed and scalable genomic analyses It started in June with the publication of our beloved GenPipes framework and set of NGS data analysis pipelines in GigaScience. We use these pipelines on a daily basis for data production and routine analysis and hope the community [Read more] COVID-19 Resources Canada Canadian Centre for Computational Genomicshas been part of a group of volunteer researchers, students, activists and web developers, led by Guillaume Bourque of McGill Universityand Tara Moriarty of the University of Toronto, who created COVID-19 Resources Canada a website to facilitate the sharing of information, expertise [Read more] Methylation signatures investigations The C3G Toronto node has also been involved in two projects to investigate methylation signatures for specific conditions. We have recently published a manuscript in BMC Medical Genomics in which we describe specific DNA methylation signatures for Nicolaides-Baraitser syndrome (NBS), a rare childhood condition that affects [Read more] Altered differentiation is central to HIV-specific CD4+ T cell dysfunction in progressive disease Another noteworthy publication to which C3G members contributed as authors was published in Nature Immunology this summer. An important focus of the study was the comparison of HIV-specific CD4 T-cells subpopulations from patients who have undergone [Read more] GSoC 2019 is over! Again this year, C3G was a Google Summer of Code organization. For people unfamiliar with it, GSoC is in Google’s own words: ” a global program that matches students up with open source, free software and technology-related organizations to write code and get paid to [Read more] Altered microbiome composition in individuals with fibromyalgia This summer has also been very special for C3G’s metagenome specialist Emmanuel Gonzalez with a publication in Painhighlighting a strong potential link between the microbiome and fibromyalgia, a terrible and elusive disorder affecting a large fraction of the population. This study drew [Read more] Infant Glioma: Characterizing the landscape of genetic drivers and their clinical impact Recently published in [Nature Communications], this paper presents work by members of the C3G Toronto node that integrates genomic and transcriptomic analyses to assess the molecular and clinical features of infant glioma patients. Examining single nucleotide variants, [Read more]ForCasT
Why better Data Sharing means better health Care
Covid-19 updates at C3G
GenPipes: an open-source framework
COVID-19 Resources Canada
Methylation signatures investigations
Altered differentiation is central to HIV-specific CD4
GSoC 2019
Fibromyalgia
Characterizing the landscape of genetic drivers and their clinical impact
BLOGUEMary Ann Kizhakechethipuza2021-09-20T12:18:42-04:00
